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Accelerating dosimetry planning and improving Y-90 SIRT workflows

Simplicit90Y is a customized, easy-to-use dosimetry software developed for accelerating dosimetry planning and improving Y-90 SIRT workflows.


Multi modal images

Simplicit90Y allows you to easily incorporate multimodal images with a range of high-performance registration tools, all with one common interface.
Coupled with automated and semi-automated tools for segmentation, this reduces inter-user variability and improves dosimetry consistency and planning confidence.

  • Multimodal image fusion and registration

  • Automated tools for liver segmentation on CT and MR

  • Intuitive LSF calculation tools

  • Dosimetric estimates with one-compartment, multi-compartment and voxel-wise techniques

  • Pre- and post-treatment dosimetry

  • Comprehensive reports creation


Simplicit90Y in action

Multicenter trials highlight the benefits of personalized dosimetry with Simplicit90Y

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Personalized versus standard dosimetry approach of selective internal radiation therapy in patients with locally advanced hepatocellular carcinoma (DOSISPHERE-01): a randomized, multicenter, open-label phase 2 trial
This study aimed to compare the efficacy of a personalized versus standard dosimetry approach of selective internal radiation therapy with yttrium-90-loaded glass microspheres in patients with hepatocellular carcinoma.
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Simplicit90Y used to support dosimetry workflow with CBCT
This study shows an example of how Simplicit90Y can be used to support Y-90 dosimetry on cone-beam computed tomography (CBCT) data. The protocol included automatic registration and segmentation on CBCT as well as three-dimensional dosimetry data at a voxel level
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Simplicit90Y used to support assessment of the future remnant liver
This study shows how Simplicit90Y was used to assess how radioembolization induces regional changes in liver function that are accurately detected by hepatobiliary scintigraphy (HBS).
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